India approves world's first DNA injection

Yes, everything happens fast. Another experimental miracle pot has appeared and the show is on its way. This is a three-dose substance called ZyCoV-D

Official media report that the injection stopped the symptoms in 66% of the injectors, according to a temporary study organized by the manufacturer Cadila Healthcare. The company plans to produce 120 million doses annually. As was the case with mRNA injections, which have never been used in humans, the same is written here. They work on animals, but so far never on humans. Now all of a sudden it starts working.

Three vaccines have already been approved in India, but none of them are Western manufacturers - Covishield, Covaxin and Sputnik. However, the vaccination rate in India is still very low - only 5% are fully injected and 22% have received a single dose.

Cadila Healthcare has organized the largest clinical trial ever in India, with 28,000 participants in more than 50 different centers. This is the first time that kovid vaccine has been tested in India on young people - it also includes 1,000 young people aged 12-18. Logically, it is also considered 'safe and effective' in this group.

The main argument is that the vaccine was tested in the second wave of the 'deadly virus'. Therefore, the manufacturer believes that it also provides efficacy against the new Delta variant. If all this works, then injecting will become logistically simpler in the future, says Shahid Jameel, one of India's best-known virologists.

How does DNA injection work? Both RNA and DNA are building blocks of life. These are molecules that carry genetic information that is passed down through the generations. DNA injection also does the same thing as an RNA vaccine - it 'teaches' the body to fight a real virus. Which, by the way, is nowhere to be found. But now - ZycoV-D uses DNA plasmids that contain genetic information and is inserted between the layers of the skin. They carry information to the cells and produce peak protein - all the same as other vaccines, making the cells a site of toxic peak protein and creating ‘antibodies’.

Until now, DNA vaccines have only been approved for animals, such as horses and dogs in the United States. But there are now more than 160 different DNA injection tests on people in the United States alone - not all of them are for the virus, most are against cancer and 1/3 even against HIV.

But this Indian vaccine is also the first to use the new input technology and is needle-free. It is injected differently, with a narrow jet of liquid that penetrates the skin and injects it into the desired layer. The advantage of DNA injections is that they are cheap, safe and stable - says kovid science. They can be stored in an ordinary refrigerator, but Cadila Healthcare claims that their vaccine works even after 3 months at +25 degrees - this is what they once need for massive Indian injections. But then why haven't people been like this so far?

According to the article, the problem was in the delivery system, because it is very difficult to get this DNA plasmid into the nucleus of a human cell - because RNA vaccines do not have such a requirement - they also work outside the cell. To be more precise, it does not work, as evidenced by what is really happening in Israel and elsewhere.

But there are already three doses for this miracle vaccine, and it is considered one of the disadvantages, and how it will be next and how many additional doses will be needed for this experiment, I do not even want to think about it at the moment.